ADJUVANT CHEMOTHERAPY FOR STAGE II COLON CANCER

That can help doctors give their patients the best possible care, the U . s citizens Society of Clinical Oncology (ASCO) developed evidence-based tips for adjuvant chemotherapy for stage II colon cancer. Information for patients is based on ASCO’s recommendations.

Key Messages:

  • Coda chemotherapy is additional treatment given after surgery to the risk of the cancer returning.
  • Chemotherapy after colon cancer treatment simply recommended for routine use in patients with stage II colon cancer.
  • Talk with your doctor about the risks and primary advantages of adjuvant chemotherapy.
  • Background

Colon cancer is a disease that the normal cells in the lining of the colon begin to improvement in a way that causes them to grow uncontrollably and form scores of cells, called a tumor. If a tumor is large enough, it will interfere with the normal function of the colon, such as digesting food and passing waste. The colon is part of the large will certainly; the rectum is the last few inches of the colon, and then the treatment of tumors in this area may differ from other areas of the colon.

Staging is a way of describing the cancer, such as it’s size, and whether or where the cancer has spread. Melanoma may spread through the blood or lymphatic system. The very lymphatic system is part of the immune system and drains fluid right from body tissues through a series of tubes. Lymphatic fluid is certainly filtered in small , bean-shaped organs called lymph nodes. When cancer cells travel in the lymphatic system, they will become trapped in the lymph nodes. Stage II colon melanoma means that the cancer has spread through the wall of the intestinal tract and may have spread to nearby tissues or body parts, but has not spread to the nearby lymph nodes.

Side issue Therapy

Adjuvant therapy is additional treatment given after surgical procedures to reduce the risk that the cancer will come back. Chemotherapy would be the use of drugs to treat cancer.

Patients may receive chemotherapy just as one injection into a vein or as a pill that can be undertaken by mouth. Some drugs are given continuously over several days or weeks; some are given several times a week. Adjuvant chemotherapy for digestive tract cancer usually includes a drug called fluorouracil (5-FU). Leucovorin (Wellcovorin), irinotecan (Camptosar), and oxaliplatin (Eloxatin) may be assigned in addition to 5-FU. Most adjuvant chemotherapy treatment schedules last for about six to eight months.

However , chemotherapy can damage healthy units along with cancer cells. Patients receiving chemotherapy may the actual following side effects, especially if more than one drug is used. These side-effects can usually be treated and often go away once treatment is ended. However , in some patients, symptoms of peripheral neuropathy may keep going.

  • Tiredness (fatigue)
  • Nausea and vomiting
  • Diarrhea and abdomen cramping
  • Low white blood cell count
  • Mouth sores (mucositis)
  • Myelosuppression, which means the bone marrow stops producing blood cells
  • Nerve damage (peripheral neuropathy), such as tingling, numbness, and also pain in the hands and feet

Chemotherapy affects consumers in different ways. Some patients experience mild side effects, whilst some require hospitalization because of these side effects. Occasionally, these adverse reactions become life-threatening. The risk of dying from the adjuvant chemotherapy is really low, less than 1%, but may be higher in persons who are older and have other health issues. Talk with your doctor concerning risk of side effects from adjuvant chemotherapy, how long they could survive, and how to treat them.

Recommendations

Adjuvant chemotherapy is not highly recommended for routine use in patients with stage II intestines cancer. However , in certain situations, it may be reasonable for you with your doctor to consider adjuvant chemotherapy. This recommendation is based on the end result of clinical trials, which show that patients who seem to receive adjuvant chemotherapy have about a 4% to 5% greater chance of survival at five years after surgery treatment, compared with patients who did not receive adjuvant chemotherapy. (The exact benefit is not known with certainty because deficiency of stage II patients have been included in clinical trials. )

In other words, patients who receive chemotherapy after colon cancer surgery use a small chance of reducing the risk of their cancer coming back equated with patients who do not receive the extra treatment. Given the potential risks of chemotherapy, patients should talk to their doctors around whether this small benefit is worth the risk of extra medication.

What This Means for Patients

Adjuvant chemotherapy for stage 2 colon cancer may lower the risk of the cancer finding its way back, but is also associated with potentially serious side effects. To learn more about coda chemotherapy for colon cancer, talk with your doctor about the cycle of your cancer, your medical history, your overall health, and the risks and even benefits of adjuvant treatment, including the potential side effects.

Questions to Talk to the Doctor

What is the stage of my cancer?

  • If I elect to receive adjuvant chemotherapy, what is my prognosis (chance for recovery)?
  • If I decide not to receive adjuvant chemotherapy, what’s my prognosis?
  • What are the drugs, timing, duration, and pencil in of the adjuvant treatment I might consider?
  • What are the benefits of side issue chemotherapy?
  • What are the side effects and other risks of adjuvant chemotherapy?
  • Are there any medical factors related to my overall health that would become a success harder for me to undergo adjuvant therapy?
  • Are there specialized gear that can help estimate survival based on my personal information?
  • Am I able to get a clinical trial?
  • Where can I find more information?

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